This also fixes the clipping issues with the Pakal Chest Plate and Kuva Leg Plates.
#How to patch spore 2018 Patch
If we successfully replicate the same results in human trials, the patch could become a good option for eye diseases such as glaucoma and diabetic retinopathy that require long-term management at home,” said Chen.Ĭhen added that the team has filed a patent for their invention and is currently working on further improving the eye patch technology. “The microneedles are made of a substance found naturally in the body and we have shown in lab tests on mice that they are painless and minimally invasive. The researchers reported that there was no puncture on the cornea after a week, suggesting that the microneedles were strong enough to penetrate the cornea, but not so stiff as to cause damage to it. In mice suffering from corneal vascularization, where blood vessels in the cornea obstruct vision, a single application of the patch was 90 percent more effective in alleviating the condition than applying a single eye drop containing ten times the drug content. They found that the drug-containing microneedles detached and stayed in the cornea, releasing the drug over time as they dissolved. Testing their invention in mice, the researchers pressed the patch onto the eye surface briefly and gently. A modified version of hyaluronic acid is added to form a second layer of the needle, which slows down the rate at which the needle degrades, thereby ensuring prolonged release of the drug.
Each needle, thinner than a strand of hair, is made of hyaluronic acid-a substance found in the eye-and is shaped like a pyramid for optimal tissue penetration. In the present study, researchers led by NTU Singapore Professor Chen Peng developed a proof-of-concept patch covered with biodegradable microneedles that allows controlled drug delivery to the eye. As a result, some patients are unable to keep up with the prescribed regime for their eye ailments, many of which require long-term management. While doctors may sometimes prescribe eye injections, such treatments can be painful and carry a risk of infection and eye damage. They reported their results in Nature Communications.Ĭurrently, eye diseases such as glaucoma and macular degeneration are treated using localized methods such as eye drops and ointments, which are hindered by the eye’s natural defenses-tears and blinking. 29, 2018) – A research group at Nanyang Technological University, Singapore, has developed a ‘contact lens’ that could provide a painless and efficient alternative to eye injections.
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